pharmacokinetics and dynamics calculator

#PHARMACOKINETICS AND DYNAMICS CALCULATOR PROFESSIONAL#

^ MacKerell AD Jr, Feig M, Brooks III CL (2004).'All-atom empirical potential for molecular modeling and dynamics studies of proteins'. 'Theoretical studies of hydrogen bonding'. 'CHARMM: The biomolecular simulation program'. ^ Brooks BR, Brooks CL 3rd, Mackerell AD Jr, Nilsson L, Petrella RJ, Roux B, Won Y, Archontis G, Bartels C, Boresch S, Caflisch A, Caves L, Cui Q, Dinner AR, Feig M, Fischer S, Gao J, Hodoscek M, Im W, Kuczera K, Lazaridis T, Ma J, Ovchinnikov V, Paci E, Pastor RW, Post CB, Pu JZ, Schaefer M, Tidor B, Venable RM, Woodcock HL, Wu X, Yang W, York DM, Karplus M (29 July 2009).V = ∑ b o n d s k b ( b − b 0 ) 2 + ∑ a n g l e s k θ ( θ − θ 0 ) 2 + ∑ d i h e d r a l s k ϕ + ∑ i m p r o p e r s k ω ( ω − ω 0 ) 2 + ∑ U r e y − B r a d l e y k u ( u − u 0 ) 2 + ∑ n o n b o n d e d ( ϵ i j + q i q j ϵ r r i j ) : CS1 maint: multiple names: authors list ( link) The CHARMM22 force field has the following potential energy function: In 2006, a special version of CHARMM22/CMAP was reparametrized for consistent use with implicit solvent GBSW. Nevertheless, it is often used with implicit solvents. Furthermore, CHARMM22 is parametrized for the TIP3P explicit water model. Modeling and Simulation (M&S) group in the Pharmacokinetics, Dynamics. In the CHARMM22 protein force field, the atomic partial charges were derived from quantum chemical calculations of the interactions between model compounds and water. Upon completion of this course of study, graduates from the NP track are eligible to take the Pediatric Nurse Practitioner certification exam given by the Pediatric Nursing Certification Board (PNCB).The CHARMM force fields for proteins include: united-atom (sometimes termed extended atom) CHARMM19, all-atom CHARMM22 and its dihedral potential corrected variant CHARMM22/CMAP, as well as later versions CHARMM27 and CHARMM36 and various modifications such as CHARMM36m and CHARMM36IDPSFF. Mary Thompson, PhD, RN, CPNP-PC, for the Pediatric Specialty Research (manage conditions using evidence-based research for body systems and problem areas, outcomes evaluation continuous process improvement).

#PHARMACOKINETICS AND DYNAMICS CALCULATOR PROFESSIONAL#

Professional issues (ethics, scope of advanced practice nursing, access to care).Practitioner-patient relationship (cultural and spiritual competence, communication skills, teaching/coaching, patient education, patient advocacy).Pharmacology (pharmacokinetics/dynamics indications, side effects, drug interactions & contraindications, patient education).Clinical management of acute and chronic illness/conditions (current standards of practice related to management of body systems and problem areas, clinical practice guidelines, pharmacotherapeutics, clinical therapeutics, clinical decision-making, patient safety, developmental, family, and health related theory application).Assessment of acute and chronic illness (epidemiology/disease risk and control, anatomy and pathophysiology, psychopathology, diagnostic reasoning including differential diagnoses, health assessment).Health promotion and disease prevention (epidemiology/risk analysis, genetics, risk reduction, health behavior guidelines, biological considerations, growth and development, screening tests, wellness assessment).Knowledge and skills preparation include: The Pediatric track emphasizes diagnosing and managing common primary care problems through comprehensive physical and psychosocial assessment, decision-making / diagnostic reasoning processes, and developmental health maintenance, including health promotion and disease prevention.įocusing on a collaborative model for providing holistic care, this track prepares you for practice in a variety of hospital and community-based practice settings, including community health clinics, private medical practices, and specialty clinics. Preparing students to provide comprehensive wellness care, as well as acute, episodic, and chronic care, this track encourages students to assume a leadership role in addressing health care trends, professional issues, role development, and research. The Pediatric advanced practice nursing specialty prepares you to be the principal provider of primary health care for children from birth through 21 years of age.

Pharmacokinetics and dynamics calculator